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Detects reliably below 0.1% mutant DNA by real-time PCR

QClamp® JAK2 Mutation Test

The QClamp® JAK2 Mutation Test in Codon 617 is a real-time PCR assay for the detection of somatic mutations in and near JAK2 codon 617 in Exon 14 in the JAK2 tyrosine kinase gene, using purified DNA extracted from FFPE (formalin fixed paraffin embedded), cells or tissue. The kit identifies the presence or absence of mutations in the targeted regions but does not specify the exact nature of the mutation. The codon specific detection kits are designed to detect any mutation at or near the stated codon site without specifying the exact nucleotide change.

HIGHLIGHTS

• Sample Ready: Suitable for FFPE, cell or tissue
• Ultra-Sensitive: Detects below 0.1% mutant DNA by real-time PCR
• Rapid: Streamlined workflow with less than 4 hours turnaround time
• Versatile: Works with most PCR machines
• Reproducible: Robust XNA-PCR technology minimizing variability

List of mutations and cosmic identities found in JAK2

Exon  Amino Acid Change Nucleotide change Cosmic No.
14 V617>F 1849G>T  12600

Product specifications

Specification QClamp® JAK2 Codon Specific Mutation Test
Intended UseFor In Vitro Diagnostic Use (CE/IVD) or For Research Use
Sample TypeFFPE, Cells or Tissues
Pack Size10 Samples, 30 Samples and 60 Samples
Validated InstrumentsABI 7500, ABI 7500FAST, ABI 7900, ABI StepOnePlus, Qiagen Rotor-Gene Q, Roche LightCycler LC96, Roche LightCycler 480 II
Detection ChannelFAM; HEX
Turnaround TimeLess than 4 hours
StabilityStable for 12 months at -25 ℃ to -15 ℃

Ordering information

Product NameCatalog # (RUO)Catalog # (CE/IVD)
QClamp® JAK2 Codon Specific Mutation Test in Codon 617 (10 Samples)DC-10-1037R DC-10-1037
QClamp® JAK2 Codon Specific Mutation Test in Codon 617 (30 Samples)DC-10-0166RDC-10-0166
QClamp® JAK2 Codon Specific Mutation Test in Codon 617 (60 Samples)DC-10-0165R DC-10-0165

Note: RUO (Research Use Only) products are not for use in diagnostic procedures. CE/IVD products are intended for use in diagnostic procedures.