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QClamp® PIK3CA Codon Specific Mutation Test in Codons 542, 545 & 1047 (CE/IVD)

QClamp® PIK3CA Mutation Test

The QClamp® PIK3CA Mutation Test in Codons 542, 545, & 1047 is a real-time qualitative PCR assay for the detection of somatic mutations in and near PIK3CA Codons 542 and 545 in Exon 9 and Codon 1047 in Exon 20 in the human PIK3CA gene, using purified DNA extracted from FFPE (formalin fixed paraffin embedded), cells or tissue. The kit identifies the presence or absence of mutations in the targeted regions but does not specify the exact nature of the mutation. The codon specific detection kits are designed to detect any mutation at or near the stated codon site without specifying the exact nucleotide change.

Ordering information

Product NameCatalog # (RUO)Catalog # (CE/IVD)
QClamp® PIK3CA Codon Specific Mutation Test in Codons 542, 545 & 1047 (10 Samples)DC-10-0153RDC-10-0153
QClamp® PIK3CA Codon Specific Mutation Test in Codons 542, 545 & 1047 (30 Samples)DC-10-1072R DC-10-1072
QClamp® PIK3CA Codon Specific Mutation Test in Codons 542, 545 & 1047 (60 Samples)DC-10-1075R DC-10-1075
*RUO (Research Use Only) products are not for use in diagnostic procedures.

List of mutations and cosmic identities found in PIK3CA

Exon Amino Acid Change Nucleotide change Cosmic No.
9 E542>K c.1624G>A 760
E542>G c.1625A>G 761
E542>V c.1625A>T 762
E545>K c.1633G>A 763
E545>G c.1634A>G 764
E545>D c.1635G>T 765
20 H1047>Y c.3139C>T 774
H1047>L c.3140A>T 776
H1047>R c.3140A>G 775