Assay Detects Precancerous Colorectal Cancer Lesions & Mutations
Written by Chris Wolskiat Clinical Lab Products
NGS test for colorectal cancer to guide targeted therapy
Colorectal cancer (CRC) can develop from germline genetic mutations inherited from family or somatic mutations developed later in life. Our Optiseq™ colorectal cancer NGS for mutation detection panel covers genes associated with both hereditary and somatic mutations...
Detection of ROS1, RET, and ALK fusions in non-small cell lung cancer
ROS1 (c-ros oncogene 1), RET (rearranged during transfection), and ALK (anaplastic lymphoma kinase) are receptors of tyrosine kinases that play important roles in cell growth and differentiation. ROS1, RET or ALK fusion is formed by chromosomal rearrangements that...
Who should be tested for VEXAS syndrome?
As a relatively newly discovered autoinflammatory disease, VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) syndrome is associated with mutations in the UBA1 gene. Diagnosis of the disease relies on the testing of genetic mutation in patients. What are...
Genetic Testing for the VEXAS Syndrome
Diagnosis of the VEXAS syndrome improves medical management of the disease and provides more effective treatment of the disease, although there is no cure currently. The diagnosis relies on the VEXAS syndrome genetic testing, a test for a mutation present in the UBA1...
What is VEXAS syndrome?
VEXAS syndrome, which stands for "Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic," is a rare and recently identified, chronically progressive autoinflammatory disorder. It was first described by Dr. Beck in a study published in the New England Journal of...
Dealing with the Respiratory Viruses that Cause Covid-19 or Flu
Influenza and COVID-19: what are they in common? Currently, the two most important respiratory viruses the healthcare authority is paying attention to are SARS-COV-2 (causing COVID-19) and influenza A and B viruses (Flu A and B). The Flu A and B viruses (named by the...